Condition:
The purpose of this study is to determine whether dynamic contrast enhanced MRI (DCE MRI) and high diffusion weighting MRI may be used to distinguish between favorable and unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be correlated with histopathologic findings and clinical responses to radiation therapy with or without chemotherapy.
Dates: November 2006 -
Study Status: Recruiting
Ages Eligible: 18 Years - 80 Years
Gender Eligible: Both
Inclusion Criteria:
- The presence of a primary brain tumor that cannot be completely resected that
requires radiation therapy with or without chemotherapy.
Exclusion Criteria:
- Patients who do not have a primary brain tumor or who are unable to tolerate the
environment of the MRI scanner
Sponsor:
First Received: January 2, 2008
Last Updated: March 9, 2009
Clinicaltrials.gov ID:
NCT00589095
Study HIC # 0606001531
Condition:
Intervention: Other: dynamic contrast enhanced magnetic resonance imaging
The purpose of this study is to determine whether dynamic contrast enhanced MRI (DCE MRI) and high diffusion weighting MRI may be used to distinguish between favorable and unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be correlated with histopathologic findings and clinical responses to radiation therapy with or without chemotherapy.
Dates: November 2006 -
Study Status: Recruiting
Ages Eligible: 18 Years - 80 Years
Gender Eligible: Both
Inclusion Criteria:
- The presence of a primary brain tumor that cannot be completely resected that
requires radiation therapy with or without chemotherapy.
Exclusion Criteria:
- Patients who do not have a primary brain tumor or who are unable to tolerate the
environment of the MRI scanner
Sponsor:
First Received: January 2, 2008
Last Updated: March 9, 2009
Clinicaltrials.gov ID:
NCT00589095
Study HIC # 0606001531
Jonathan Knisely, MD
203-785-6128
jonathan.knisely@yale.edu
Knisely, Jonathan P. S.
Principal Investigator
HIC # 0805003779