Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)

Diseases and Conditions Researched

Polycystic Ovarian Syndrome

What is the purpose of this trial?

The investigators aim is to conduct a prospective un-blinded pilot study of premenopausal women diagnosed with Polycystic Ovarian Syndrome (PCOS), defined using criteria developed at the 1990 NICHD conference on PCOS, undergoing treatment for ovulation induction with Metformin. We propose that improving insulin sensitivity with use of Metformin in women diagnosed with PCOS has facilitatory influences on the uterine endometrium.



Participation Guidelines

Age: 18 Years - 42 Years
Gender: Female

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Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Yale University
Dates: February 16, 2010
Last Updated: February 21, 2012
Study HIC#: 0905005203
Clinicaltrials.gov ID: NCT01070160